报告名称：Inference in a mixture additive hazards cure model

主办单位：永利集团88304官网

报告专家：何海金

专家所在单位：深圳大学

报告时间：2020年11月13日10:00-11:00

报告地点：腾讯会议（会议ID：633 544 900）

专家简介：何海金，统计学博士，深圳大学讲师，主要研究方向包括生存分析、潜变量模型、半参数模型等。何海金博士于2014年在香港中文大学获得统计学博士学位，2015年至今在深圳大学数学与统计学院担任讲师。在国际著名的统计SCI期刊《Journal of the American Statistical Association》、《Statistica Sinica》、《Statistics in Medicine》、《Computational Statistics and Data Analysis》等发表研究论文若干篇。

报告摘要：We propose a mixture additive hazards (AH) cure model for survival data with a cure fraction. The proposed model integrates a logistic regression model for the proportion of patients cured of disease and an AH model for the uncured patients. Generalized estimating equations are developed for parameter estimation, and the asymptotic properties of the resulting estimators are established. In addition, model-checking methods are presented to assess the adequacy of the model. The finite-sample performance of the proposed method is evaluated through simulation studies. An application to a human papillomavirus positive oropharyngeal cancer study is conducted to illustrate the proposed method.

邀请人：刘展